Abstract: Chemical examination of a Chinese mangrove plant Excoecaria agallocha L. led to the isolations of a new glucoside named 1-(3,5-dimethoxy-4-hydroxybenzyl)-6-O-galloyl-1-O-β-D-glucopyranoside (1), together with 10 known glycosides including 3,5-dimethoxy-4-hydroxybenzyl-1-O-β-D-glucopyranoside (2), hydrangeifolin I (3), (2-methoxy-5-hydroxymethyl-phenyl)-1-O-β-D-(6-O-galloyl) glucopyranoside (4), (3,5-dimethoxy-4-hydroxyphenyl)-1-O-β-D-(6-O-galloyl) glucopyranoside (5), 3-methoxy-4-hydroxyphenyl 1-O-β-D-(6-O-galloyl) glucopyranoside (6), 3,4,5-trimethoxyphenyl-(6-O-galloyl)-O-β-D-glucopyranoside (7), koaburaside (8), koaburaside monomethyl ether (9), cuneatasides D (10), and (E)-isosyringin (11). Their structures were determined through the extensive spectroscopic analysis and comparison with the reported data in literature. Compounds 2-6, 8-11 were isolated from the genus Excoecaria for the first time.

Key words: Excoecaria agallocha, Phenolic glucopyranoside, Chemical components, Mangrove plant