Determination of the heavy metal content of Entoban herbal medicinal product

doi:10.5246/jcps.2015.11.097

Journal of Chinese Pharmaceutical Sciences ›› 2015, Vol. 24 ›› Issue (11): 764-769.DOI: 10.5246/jcps.2015.11.097

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Determination of the heavy metal content of Entoban herbal medicinal product

Sadia Shakeel², Zeeshan Ahmed Sheikh¹, Khan Usmanghani^1,3, Nadeem Khalid¹, Zafar Ali¹, Somia Gul³, Safila Naveed^3*

1. Herbion Pakistan (Pvt.) Ltd., Karachi, Pakistan 75400
2. Faculty of Pharmacy, Dow University of Health Sciences, Karachi, Pakistan 74200
3. Faculty of Pharmacy Jinnah University for Women Karachi, Pakistan 74600

Received:2015-08-15 Revised:2015-09-10 Online:2015-11-20 Published:2015-09-26
Contact: Tel.: 00923002621917, E-mail: safila117@yahoo.com

Abstract

Abstract:

The levels of As, Cd, Pb and Hg were investigated in the medicinal herbal syrup Entoban, which is widely used in the management of non-specific diarrhea and acute intestinal infections of various etiologies. The ingredients in Entoban syrup include 6 potent herbal drugs: Aegle marmelose, Berberis aristata, Butea frondosa, Holarrhena antidysenterica, Myrtus communis, and Quercus infectoria. Entoban medicinal plant syrup was analyzed for As, Cd, Pb and Hg by flame atomic absorption spectroscopy (FAAS). Contents of heavy metals in the examined samples were in the range: As (0.074–10.0 ppm); Cd (0.020–0.3 ppm); Pb (0.00–10.0 ppm) and Hg (0.00–1.0 ppm). Results were compared with permissible limit acceptability intake (AHPA). According to determined amounts of heavy metals, the investigated Entoban syrup samples were validated and considered safe for human consumption.

Key words: Heavy metals, Flame atomic absorption spectroscopy, Medicinal plants, Entoban syrup

CLC Number:

R284

Supporting:

Sadia Shakeel, Zeeshan Ahmed Sheikh, Khan Usmanghani, Somia Gul, Safila Naveed. Determination of the heavy metal content of Entoban herbal medicinal product[J]. Journal of Chinese Pharmaceutical Sciences, 2015, 24(11): 764-769.

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Determination of the heavy metal content of Entoban herbal medicinal product

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