A systematic review of hyaluronic acid for burn treatment

doi:10.5246/jcps.2013.03.040

Abstract

Abstract:

To explore the efficiency and safety of hyaluronic acid for burn victims, we searched for all the relative references, selected the references according to the inclusion criterion, assessed them critically and conducted Meta-analysis. The experimental group and the control groups have statistically significant difference in the average time for wound healing. If we make subgroup analysis according to the origin, the outcomes of both foreign study and Chinese study have statistical significance. No statistically significant difference is revealed in the incidence of adverse reaction. In terms of the healing time for diverse burn wounds, statistically significant difference exists in the superficial second-degree burn. There is no statistically significant difference in deep second-degree burn, skin-grafting sites and donor sites. It revealed that hyaluronic acid can accelerate the healing of burn on skin, especially for superficial second-degree burn. And its adverse reaction by external use is negligible.

Key words: Hyaluronic acid, Burn, Systematic review, Meta-analysis

CLC Number:

Supporting:

Min Yang, Jing Lu, Xuehua Jiang^*
. A systematic review of hyaluronic acid for burn treatment [J]. , DOI: 10.5246/jcps.2013.03.040.

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