Traditional Chinese Medicine (TCM) has been utilized in China for thousands of years to treat and prevent various diseases, with recent research highlighting microRNAs (miRNAs) in herbal decoctions as key bioactive components. The extracts of fresh pig spleen (PAT), encapsulated with cytidinyl lipid DNCA and cationic lipid CLD, demonstrate significant anti-tumor(A549) effect by silencing DEPDC1 mRNA and promoting the maturation of bone marrow-derived dendritic cells (BMDCs), etc.
Yu, X.T. et al. / J. Chin. Pharm. Sci. 2025, 34 (1), 14–27.