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马兜铃科植物Aristolochia triangularis的生物碱成分研究

林文翰*, 付宏征, 羽野芳生, 野村太郎   

  1. 1. 北京医科大学天然药物与仿生药物国家重点实验室, 北京 100083
    2. 日本东邦大学部, 千叶县大久保2-2-1 日本
  • 收稿日期:1996-07-15 修回日期:1997-01-02 出版日期:1997-03-15 发布日期:1997-03-15
  • 通讯作者: 林文翰*

Alkaloids from the Roots of Aristolochia Triangularis (I)

Wen-Han Lin*, Hong-Zheng Fu, Yoshio Hano, Taro Nomura   

  1. 1. National Laboratories of Natural and Biomimetic Laboratories; Beijing Medical University; Beijing 100083
    2. Faculty of Pharmaceutical Sciences; Toho University
  • Received:1996-07-15 Revised:1997-01-02 Online:1997-03-15 Published:1997-03-15
  • Contact: Wen-Han Lin*

摘要: 从马兜铃科植物Aristolochia triangularis的根部分离出十五个生物碱成分。其中两种成分triangularine-Atriangularine-B系新生物碱, 三种系阿卟啡类季铵碱。这些化合物的结构经各种波谱(IR, UV, MS, 2D NMR) 解析和化学转化技术得以确定。

关键词: Aristolochia triangularis, 马兜铃碱-A, 马兜铃碱-B, 马兜铃内酰胺, 4,5-二氧阿卟啡

Abstract: From the roots of Aristolochia triangularis, two new alkaloids triangularine-A and triangularine-B together with thirteen known alkaloids namely aristololactam AII, AIIIa, AIA, Ia, IIA, BII, CII, cepharadione A, 4,5-dioxodehydroasimilobine; aristolochic acid-D (IVa), magnoflorine; N,N-dimethyllindcarpine and oblongine were isolated, their structures were identified by means of spectral analysis and chemical conversion.

Key words: Aristolochia Triangularis, Triangularine-A, Triangularine-B, Aristololactam, 4,5-Dioxoaporphine

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