红参中的一种新氨基酸衍生物

红参中的一种新氨基酸衍生物

郑毅男, 奥田拓道, 韩立坤, 向兰, 松浦幸永, 高久武司, 龟田健治

1. 吉林农业大学, 长春 130118;
2. 爱媛大学医学部, 791-02, 日本

收稿日期:1996-07-17 修回日期:1997-10-13 出版日期:1998-03-15 发布日期:1998-03-15

A New Amino Acid Derivative from Red Ginseng

Yi-Nan Zheng, H Okuda, Li-Kun Han, Lan Xiang, Y Matsuura, T Takaku, K Kameda

1. Jilin Agricultural University, Changchun 130118;
2. School of Medicine, Ehime University, Japan 791-02

Received:1996-07-17 Revised:1997-10-13 Online:1998-03-15 Published:1998-03-15

摘要/Abstract

摘要： 红参水提液经聚丙烯酰胺(Bio-gel P-2)柱层析,分离得到五个茚三酮反应阳性物质。其中一个为已知化合物—精氨酸(1), 另一个为新化合物—精氨酸双糖甙2), 根据红外、紫外、质谱、氢谱及碳谱解析, 推定其为1'-(精氨酸-Nα基)-1'-去氧-4'-O-(α-D-吡喃葡萄糖基)-D-果糖。并用半合成法进一步确证其结构。化合物3, 4和5的结构正在研究中。

关键词: 红参, 精氨酸双糖甙

Abstract: Five ninhydrin-positive compounds were isolated from the water extract of red ginseng through the Bio-gel P-2 column chromatography. One compound is known as arginine. Another compound is a new substance which is determined as 1'-Nα-arginine-1'-deoxy-4'-O-(α-D-glucopyranosyl)-D-fructose (AFG) through the analysis of ¹³C NMR, ¹H NMR, IR and UV spectra. Its structure is also verified through the reaction of maltose and arginine. The structures of compounds 3, 4 and 5 are being researched.

Key words: Red ginseng, Argininyl-fructosyl-glucose (AFG)

Supporting: ^*First published in Chinese in Acta Pharmaceutica Sinica, 1996 , 31 (3) 191~195.

郑毅男, 奥田拓道, 韩立坤, 向兰, 松浦幸永, 高久武司, 龟田健治. 红参中的一种新氨基酸衍生物[J]. .

Yi-Nan Zheng, H Okuda, Li-Kun Han, Lan Xiang, Y Matsuura, T Takaku, K Kameda. A New Amino Acid Derivative from Red Ginseng[J]. .