对叶百部的新化学成分研究

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对叶百部的新化学成分研究

林文翰, 付宏征

北京医科大学, 天然药物及仿生药物国家重点实验室, 北京, 100083

收稿日期:1998-04-05 修回日期:1998-12-12 出版日期:1999-03-15 发布日期:1999-03-15

Three New Alkaloids from the Roots of Stemona tuberosa Lour

Lin Wenhan, Fu Hongzheng

National Research Laboratortes of Natural of Natural and Biommetic Drugs,Beijing Medical University, Beijing 100083

Received:1998-04-05 Revised:1998-12-12 Online:1999-03-15 Published:1999-03-15

摘要/Abstract

摘要： 从对叶百部(Stemona tuberosa Lour)的根部分得6个生物碱,分别为对叶百部烯酮(tuberostemoenone)(1), N-氧-对叶百部碱(N-oxy-tuberostemonine)(2)异脱氢对叶百部碱(isodidehydrotuberostemonine)(3), 脱氢对叶百部碱(didehydrotuberostemonine)(4), 对叶百部酮(tuberostemonone)(5), 氧化对叶百部碱(oxotuberostemonine)(6)。它们的结构经各种波谱解析确定, 其中化合物1, 2和3为新生物碱。

关键词: 对叶百部, 对叶百部烯酮, N-氧-对叶百部碱, 异脱氢对叶百部碱

Abstract: From the roots of Stemona tuberosa Lour, three new alkaloids, named tuberostemoenone (1), N-oxy-tuberostemonine (2), isodidehydrotuberostemonine (3), together with three known alkaloids didehydrotuberostemonine (4), tuberostemonone (5) and oxotuberostemonine (6)were isolated, and their struetures were identified by various spectral analyses (IR, MS, 1H, 13C NMR,1H-1H COSY, NOESY, HMQC, HMBC) as well as 1H NMR line broadening effect.

Key words: Stemona tuberosa Lour, Tuberostemoenone, N-Oxy-tuberostemonine, Isodide-hydrotuberostemonine

Supporting:

林文翰, 付宏征. 对叶百部的新化学成分研究[J]. .

Lin Wenhan, Fu Hongzheng . Three New Alkaloids from the Roots of Stemona tuberosa Lour[J]. .