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小檗胺抗炎活性的实验研究

曹丽, 罗崇念, 卞庆亚, 肖培根   

  1. 中国医学科学院, 中国协和医科大学药用植物研究所免疫室, 北京 100094
  • 收稿日期:1998-04-04 修回日期:1998-11-18 出版日期:1999-06-15 发布日期:1999-06-15

Anti-inflammatory Activity of Berbamine

Cao Li, Luo Chongnian, Bian Qingya, Xiao Peigen   

  1. Department of Immunology, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking UnionMedical College, Beijing 100094
  • Received:1998-04-04 Revised:1998-11-18 Online:1999-06-15 Published:1999-06-15

摘要: 本文研究了小檗胺的抗炎活性, 结果表明小檗胺在25 mg·kg-1·7d50 mg·kg-1·7d剂量下对由角叉菜胶诱导的大鼠足趾肿胀及高岭土诱导的大鼠关节炎具有明显的抑制作用。实验提示小檗胺可能具有明显的抗炎活性。

关键词: 小檗胺, 抗炎活性, 抗关节炎活性

Abstract: Berbamine, a kind of alkaloid, was studied for anti-inflammatory activity. The drug was tested on carrageenan-induced rat paw oedema and kaolin-induced arthritis in rats. Berbamine has shown significant anti-inflammatory and anti-arthritic activities.

Key words: Berbamine, Anti-inflammatory activity, Anti-arthritic activity

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