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Studies on the Syntheses and Properties of 5'-Branched-sugar Isonucleosides and the Related Oligonucleotides

Tian Xiao bing, Zhang Lihe, Min Jimei   

  1. The National Key Laboratory of Natural and Biomimetic Drugs,Peking Univerit,Beijing 100083
  • 收稿日期:2001-02-04 修回日期:2001-04-05 出版日期:2001-06-15 发布日期:2001-06-15

Studies on the Syntheses and Properties of 5'-Branched-sugar Isonucleosides and the Related Oligonucleotides

Tian Xiao bing, Zhang Lihe, Min Jimei   

  1. The National Key Laboratory of Natural and Biomimetic Drugs,Peking Univerit,Beijing 100083
  • Received:2001-02-04 Revised:2001-04-05 Online:2001-06-15 Published:2001-06-15

摘要: The chemistry of nucleosides and oligonucleotides is an actively investigated field in the search for new drugs. The syntheses and the properties of isonucleosides and oligonucleotides have been investigated to improve their stability, antitumor and antiviral activities, and to reduce their toxicity.

Abstract: The chemistry of nucleosides and oligonucleotides is an actively investigated field in the search for new drugs. The syntheses and the properties of isonucleosides and oligonucleotides have been investigated to improve their stability, antitumor and antiviral activities, and to reduce their toxicity.

Supporting: