大花紫玉盘中的多氧取代环己烯衍生物

大花紫玉盘中的多氧取代环己烯衍生物

廖永红, 邹忠梅^*, 郭剑, 徐丽珍, 朱敏, 杨世林

1. 中国医学科学院中国协和医科大学药用植物研究所,北京100094;
2. 香港中文大学药学院,香港

收稿日期:2000-08-07 修回日期:2000-09-27 出版日期:2000-12-15 发布日期:2000-12-15
通讯作者: 邹忠梅*

Five Polyoxygenated Cyclohexenes from Uvaria grandiflora

Liao Yonghong, Zou Zhongmei^*, Guo Jian, Xu Lizhen, Zhu Min, Yang Shilin

1. Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100094;
2. Department of Pharmacy, The University of Chinese Hong Kong, Shatin, New Territories, Hong Kong

Received:2000-08-07 Revised:2000-09-27 Online:2000-12-15 Published:2000-12-15
Contact: Zou Zhongmei*

摘要/Abstract

摘要： 从大花紫玉盘茎中分离得到5个新的多氧取代环己烯衍生物, 根据光谱分析及与已知化合物比较确定了它们的结构, 并分别命名为大花紫玉盘酮A(2)、B(3)、C(5)、D(7)及大花紫玉盘醇J(5)。同时, 应用CD谱测定了化合物2、5、6、7 的绝对构型。

关键词: 大花紫玉盘, 多氧取代环己烯, 大花紫玉盘酮A,B,C,D, 大花紫玉盘醇J

Abstract: Five new polyoxygenated cyclohexenes, uvarigranones A (2), B (3), C (6) D (7) and uvarigranol J (5) were isolated from the stems of Uvaria grandiflora. Their structures were established on the basis of spectral data and comparison with known compounds. Among them, the absolute configurations of 2, 5, 6 and 7 were determined from their CD spectra.

Key words: Uvaria grandiflora, Uvaria grandiflora, Polyoxygenated cyclohexene, Polyoxygenated cyclohexene, Uvarigranone A,B,C,D, Uvarigranone A,B,C,D, Uvarigranol J, Uvarigranol J

Supporting: ^*This project was supported by the National Natural Sciences Foundation of China and the Chinese Doctoral Grants from the Ministry of Science and Technology, China.

廖永红, 邹忠梅^*, 郭剑, 徐丽珍, 朱敏, 杨世林. 大花紫玉盘中的多氧取代环己烯衍生物[J]. .

Liao Yonghong, Zou Zhongmei^*, Guo Jian, Xu Lizhen, Zhu Min, Yang Shilin. Five Polyoxygenated Cyclohexenes from Uvaria grandiflora[J]. .