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中国药学(英文版) ›› 2023, Vol. 32 ›› Issue (5): 426-426.

• 【新闻】 • 上一篇    

曾克武/屠鹏飞揭示毛喉素改善骨质疏松直接作用靶点

北京大学药学院 天然药物及仿生药物国家重点实验室   

  1. 北京大学药学院 天然药物及仿生药物国家重点实验室
  • 收稿日期:2023-05-10 修回日期:2023-05-11 接受日期:2023-05-11 出版日期:2023-06-02 发布日期:2023-06-02

Prof. Kewu Zeng /Prof. Pengfei Tu revealed the direct target of forskolin in improving osteoporosis

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center   

  1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center
  • Received:2023-05-10 Revised:2023-05-11 Accepted:2023-05-11 Online:2023-06-02 Published:2023-06-02

摘要:

近日, 北京大学药学院天然药物及仿生药物国家重点实验室曾克武/屠鹏飞教授团队在国际学术期刊Advanced Science上发表了题为"Allosteric Activation of Transglutaminase 2 via Inducing an 'Open' Conformation for Osteoblast Differentiation" 的研究论文, 深入阐明了天然活性分子毛喉素(forskolin)调控骨代谢进而治疗骨质疏松的分子靶点及作用机制。

Abstract:

Prof. Kewu Zeng /Prof. Pengfei Tu revealed the direct target of forskolin in improving osteoporosis.

Supporting: