Effect of calcium and soy isoflavone supplementation on bone mineral density of women with different menstrual status

doi:10.5246/jcps.2012.04.048

Effect of calcium and soy isoflavone supplementation on bone mineral
density of women with different menstrual status

Asma Rashid, Rukhshan Khurshid, Asif Hanif, Mahjabeen Saleem^*, Latif Aftab

1. Department of Pathology, Fatima Jinnah Medical College, Sir Ganga Ram Hospital, Lahore 54590, Pakistan
2. Department of Biochemistry, Fatima Jinnah Medical College, Sir Ganga Ram Hospital, Lahore 54590, Pakistan
3. Department of Medicine, Mayo hospital, Lahore 54590, Pakistan
4. Institute of Biochemistry and Biotechnology, University of the Punjab, Lahore 54590, Pakistan
5. College of Pharmacy, University of the Punjab, Lahore 54590, Pakistan

收稿日期:2012-02-24 修回日期:2012-05-08 出版日期:2012-06-25 发布日期:2012-06-25
通讯作者: Mahjabeen Saleem*

Effect of calcium and soy isoflavone supplementation on bone mineral
density of women with different menstrual status

Asma Rashid, Rukhshan Khurshid, Asif Hanif, Mahjabeen Saleem^*, Latif Aftab

1. Department of Pathology, Fatima Jinnah Medical College, Sir Ganga Ram Hospital, Lahore 54590, Pakistan
2. Department of Biochemistry, Fatima Jinnah Medical College, Sir Ganga Ram Hospital, Lahore 54590, Pakistan
3. Department of Medicine, Mayo hospital, Lahore 54590, Pakistan
4. Institute of Biochemistry and Biotechnology, University of the Punjab, Lahore 54590, Pakistan
5. College of Pharmacy, University of the Punjab, Lahore 54590, Pakistan

Received:2012-02-24 Revised:2012-05-08 Online:2012-06-25 Published:2012-06-25
Contact: Mahjabeen Saleem*

摘要/Abstract

摘要：

In order to find out the effective alternative treatments in peri- and post-menopausal women, we carried out the research. Study design was observational experimental study with duration of 6 mon. A total of 250 female subjects were included in the study. Results showed that the bone mass density or T-score in menstruating women was increased after the use of calcium and showed a highly significant difference (P<0.001). In both peri- and post-menopausal women, the values of bone mass density or T-score was non significantly increased after the use of calcium. Values of bone mass density in peri- and post-menopausal women were significantly increased (P<0.001) after the use of phytoestrogen. It is concluded that phytoestrogen is a better treatment therapy of osteopenia/osteoporosis as compared to calcium treatment. However further research is needed in large number of women to meet a better conclusion.

关键词: Calcium, Menopause, Phytoestrogen, Isoflavone supplementation

Abstract:

Key words: Calcium, Menopause, Phytoestrogen, Isoflavone supplementation

中图分类号:

R969

Supporting:

^*Corresponding author. Tel.: 92-42-99230355

Asma Rashid, Rukhshan Khurshid, Asif Hanif, Mahjabeen Saleem^*, Latif Aftab. Effect of calcium and soy isoflavone supplementation on bone mineral
density of women with different menstrual status [J]. , DOI: 10.5246/jcps.2012.04.048.

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Effect of calcium and soy isoflavone supplementation on bone mineral
density of women with different menstrual status

Effect of calcium and soy isoflavone supplementation on bone mineral
density of women with different menstrual status

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