A new linear monoterpene from the Chinese mangrove plant Cerbera manghas L.

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A new linear monoterpene from the Chinese mangrove plant Cerbera manghas L.

Xia Yu¹, Min-Juan Xu¹, Zhi-Wei Deng², Wen-Han Lin^1*

1. State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China
2. Analytical and Testing Center, Beijing Normal University, Beijing 100072, China

Received:2009-05-27 Revised:2009-08-10 Online:2009-09-15 Published:2009-09-15
Contact: Wen-Han Lin*

Abstract

Abstract:

The current study aimed to investigate the chemical components of the Chinese mangrove plant Cerbera manghas L., collected in Hainan Island. Repeated column chromatography was performed for the isolation and purification. Compounds were identified by the analysis of their 1D and 2D NMR data as well as IR and MS spectral data. A new linear monoterpene, named (2E,6S)-8-hydroxy-2-hydroxymethyl-6-methyl-2-octenoic acid (1), together with cerbinal (2), cerberidol (3), 2α,3β,24-trihydroxyolea-12en-28oic acid (4), 4,4',9,7'-tetrahydroxy-3,3'-dimethoxy-7,9'-epoxylignan (5), (-)-olovil (6), (+)-cycloolivil (7), naringenin-7-glucoside (8), aromadendrin (9), naringenine (10), and (+)-dihydroquercetin (11) were isolated from the EtOH and CH2Cl2 extracts. Compounds 4, 5, 8-11 were isolated from this plant for the first time.

Key words: Cerbera manghas L., Cerbera manghas L., Monoterpene, Monoterpene, Chemical components, Chemical components, Mangrove plant, Mangrove plant

CLC Number:

R931.77

Supporting:

Xia Yu¹, Min-Juan Xu¹, Zhi-Wei Deng², Wen-Han Lin^1* . A new linear monoterpene from the Chinese mangrove plant Cerbera manghas L. [J]. .

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