Chinese herbal enema therapy for the treatment of chronic kidney disease

doi:10.5246/jcps.2024.04.023

Abstract

Abstract:

Chronic kidney disease (CKD) has emerged as a pressing public health issue characterized by increasing incidence and mortality rates. The imperative for effective treatments to halt its progression cannot be overstated. Central to the concept of the "gut-kidney axis" is the belief that as CKD advances, uremic toxins (UTs) gradually build up, undermining the integrity of the intestinal barrier and resulting in an imbalanced gut microbiota. This dysbiosis in the gut microbiota, coupled with the compromised intestinal barriers, intensifies renal damage by furthering UT accumulation and inducing systemic inflammation. Grounded in this understanding, the use of Chinese herbal enemas has shown promising outcomes in CKD management. This review consolidates both domestic and international studies related to the "gut-kidney axis" and delves into the combination of Chinese herbal enemas with standard therapy, colon dialysis, and traditional oral Chinese medicine practices. Our aim is to shed light on novel perspectives and pinpoint emerging avenues for the evolving therapeutic landscape of CKD.

Key words: Gut-kidney axis, Chinese herbal enema, Chronic kidney disease, Research progress

Supporting:

Yonghao Sang, Jie Yun, Lijuan Dai, Liqun Song. Chinese herbal enema therapy for the treatment of chronic kidney disease[J]. Journal of Chinese Pharmaceutical Sciences, 2024, 33(4): 305-315.

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