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Journal of Chinese Pharmaceutical Sciences ›› 2019, Vol. 28 ›› Issue (10): 687-698.DOI: 10.5246/jcps.2019.10.065

• Reviews • Previous Articles     Next Articles

The naturally occurring secolignans

Ying Zhang, Xiaobo Li, Mengyue Wang*   

  1. School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China
  • Received:2019-06-12 Revised:2019-07-23 Online:2019-10-31 Published:2019-09-05
  • Contact: Tel.: +86-21-34205222; Fax: +86-21-34204804, E-mail: mywang@sjtu.edu.cn
  • About author:Dr Wang graduated from Beijing University of Traditional Chinese Medicine and was conferred the Bachelor degree in 1997. He obtained his PhD degree at School of Pharmacy, Chengdu University of Traditional Chinese Medicine in 2003. Nowadays, he serves in School of Pharmacy, Shanghai Jiao Tong University as associate professor and master tutor. For over 20 years, he has specialized in research in TCMs identification, therapeutic material basis, quality standard and quality evaluation, and has published more than 70 associated papers in domestic and international journals. Dr Wang also serves as member of the editorial board for several professional publications and has published 13 books that are related with Chinese herbal medicines.
  • Supported by:

    National Natural Science Foundation of China (Grant No. 81374067) and Shanghai Municipal Health Commission (Grant No. 2018ZY002).

Abstract:

Naturally occurring secolignans have drawn the considerable attention because of their novel structures and diverse biological activities. In recent years, various natural secolignans with extensive bioactivities have been reported in the literatures. In the present review, we summarized all the available information regarding the biosynthesis, distributions, separation methods, chemical structures, spectral characteristics, and biological activities of natural secolignans, and provided some valuable new insights for the further study.

Key words: Secolignan, Biosynthesis, Distribution, Separation, Chemical structures, Spectral characteristics, Biological activity

CLC Number: 

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