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Flavonoids from the herb of Bidens pilosa L.

Xin Tian, Si-Xiang Zhou, He-Lin Wei, Nan Hu, Zhi Dai, Zhi-Gang Liu, Zheng-Zhou Han, Peng-Fei Tu*   

  1. 1. State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing 100191, China
    2. China Resources Sanjiu Medical & Pharmaceutical Co. Ltd., Shenzhen 518110, China
  • Received:2011-05-04 Revised:2011-08-15 Online:2011-09-20 Published:2011-09-20
  • Contact: Peng-Fei Tu*

Abstract:

Chemical constituents of the whole herb of Bidens pilosa L. were investigated. By using various column chromatography (CC) and spectroscopic methods, 13 flavonoids were isolated and identified as follows: 2'-hydroxy-4,4'-dimethoxy-chalcone (1), isoliquiritigenin (2), 3,2',4'-trihydroxy-4-methoxy-chalcone (3), licochalcone A (4), 4'-O-β-D-glucopyranosyl-2',3-dihydroxy-4-methoxy-chalcone (5), butein (6), apigenin (7), luteolin (8), diosmetin (9), chrysoeriol (10), 3,5,6,7,3',4',5'-heptamethoxyflavone (11), 7-O-β-D-glucopyranosyl-5,3'-dihydroxy-3,6,4'-trimethoxyflavone (12), and sulfuretin (13). Compounds 1-5, 9, 11 were obtained from the genus Bidens for the first time.

Key words: Bidens pilosa L., Bidens, Compositae, Chemical constituents, Flavonoids, Chalcone, Flavone

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