Monitoring the quality of drugs in circulation using rapid NIR spectral comparison methods

doi:10.5246/jcps.2011.03.036

Abstract

Abstract:

Four rapid spectral comparison methods are introduced in mobile labs. They are conformity test method, general correlation coefficient method, reverse correlation coefficient method and correlation coefficient method using characteristic spectral ranges. The first method is used for tracking the movements of drugs in the distribution channels; the second is used for quickly identify new counterfeit drugs; the last two are used to screen drugs illegally added in Traditional Chinese Medicine (TCM). The applicability of the four methods is evaluated with counterfeit and authentic drugs. Our results show that these methods can be quickly constructed and used to identify counterfeit drugs accurately.

Key words: NIR, Conformity test, Correlation coefficient method, Monitor, Drug quality

CLC Number:

R917

Supporting:

Yan-Chun Feng, Xiao-Li Yang, Zhi-Hai Yang, Chang-Qin Hu^* .

Monitoring the quality of drugs in circulation using rapid NIR spectral comparison methods

[J]. , DOI: 10.5246/jcps.2011.03.036.

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Monitoring the quality of drugs in circulation using rapid NIR spectral comparison methods

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