Preparation and characterization of zinc oxide nanoparticles

doi:10.5246/jcps.2020.09.057

Abstract

Abstract:

In the present study, the zinc oxide nanoparticles (ZnO NPs) were prepared by using a sol-gel method. The characterizationof ZnO NPs, such as particle size, morphology, crystal form, optical properties and pH-responsive behavior, was carried out. The in vitro anti-tumor activity of ZnO NPs was evaluated on PC-3M and 4T1 cell lines. The results indicated that ZnO NPs were spherical NPs with uniform particle size, excellent fluorescence properties, and pH-responsive behavior. The in vitro anti-tumor activity of ZnO NPs was observed on PC-3M and 4T1 cell lines. Considering to above characteristics, ZnO NPs could be used as drug delivery carries for loading active compound performing therapeutic and diagnostic effect.

Key words: Zinc oxide nanoparticles, Sol-gel method, Size and morphology, Optical properties, In vitro anti-tumor activity

CLC Number:

R944

Supporting:

Man Liu, Shuang Zhang, Zhuoyue Li, Guangxue Wang, Jingru Wang, Xuan Zhang. Preparation and characterization of zinc oxide nanoparticles[J]. Journal of Chinese Pharmaceutical Sciences, 2020, 29(9): 617-625.

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