Microwave-assisted preparation and in vitro characterizations of doped superparamagnetic ferrite nanoclusters

doi:10.5246/jcps.2020.03.013

Abstract

Abstract:

In order to obtain nanomaterials with superparamagnetism and high saturation magnetization, Mn-doped or Zn-doped superparamagnetic ferrite nanoclusters (Mn-FNs or Zn-FNs) were prepared by microwave-assisted solvothermal method in this study. Preliminary investigations were performed by transmission electron microscopy (TEM) and dynamic light scattering (DLS) instrument to observe the morphology and measure the particle size, respectively. Afterwards, Zn-FNs were chosen to be further characterized in vitro due to their better morphology and dispersity than Mn-FNs. The subsequent characterizations included crystallinephase, metal content and magnetic properties by X-ray diffractometer (XRD), inductively coupled plasma-mass spectrometry (ICP-MS) and vibrating sample magnetometer (VSM), respectively. The results showed that Zn-FNs had a cluster-like structure assembled by multiple nanoparticles. Zn-FNs were spherical in shape with good dispersity and relatively uniform particle size. Zn was successfullydoped in Zn-FNs which demonstrated spinel structure and excellent magnetic properties. Therefore, Zn-FNs had a favorable application prospect as a new type of magnetic nanomaterial.

Key words: Microwave-assisted solvothermal method, Doped ferrite nanoclusters, In vitro characterizations

CLC Number:

R943

Supporting:

Xiaoxin Liu, Xiaoya Qin, Ziyuan Li, Tianyuan Fan. Microwave-assisted preparation and in vitro characterizations of doped superparamagnetic ferrite nanoclusters[J]. Journal of Chinese Pharmaceutical Sciences, 2020, 29(3): 153-160.

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