Chemical Constituents of Rheum tanguticum Maxim.ex Balf.

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Chemical Constituents of Rheum tanguticum Maxim.ex Balf.

JIN Wei, GE Ri-li, HUANG Zhi-qin, WEI Quan-jia, BAO Tian-you, TU Peng-fei^*

1. School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100083, China;
2. Qinghai University Medical College, Xining 810001, China;
3. Gannan Medical College, Ganzhou 341000, China

Received:2006-06-15 Revised:2006-11-10 Online:2006-12-15 Published:2006-12-15
Contact: TU Peng-fei*

Abstract

Abstract:

Aim To study the chemical constituents of the root and rhizome of Rheum tanguticum Maxim. ex Balf. Methods Chemical constituents were isolated and purified by many chromatographic methods, and their structures were elucidated by MS, NMR, and others. Results Twenty compounds were isolated and their structures were identified as β-sitosterol, chrysophanol, aloe-emodin, physcion, rhein, emodin, etc. Conclusion Among these compounds, 4-(4'-hydroxyphenyl)-2-butanone, 4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-(2''-O-cinnamoyl-6''-O-galloyl)-glucopyranoside and 4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-(2''-O-galloyl-6''-O-p-coumaroyl)-glucopyranoside were isolated from the root and rhizome of Rheum tanguticum for the first time.

Key words: Rheum tanguticum Maxim ex Balf., Rheum tanguticum Maxim ex Balf., 4-(4'-hydroxyphenyl)-2-butanone, 4-(4'-hydroxyphenyl)-2-butanone, 4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-(2''-O-cinnamoyl-6''-O-galloyl)-glucopyranoside, 4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-(2''-O-cinnamoyl-6''-O-galloyl)-glucopyranoside, 4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-(2''-O-galloyl-6''-O-p-coumaroyl)-glucopyranoside., 4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-(2''-O-galloyl-6''-O-p-coumaroyl)-glucopyranoside.

CLC Number:

Supporting:

JIN Wei, GE Ri-li, HUANG Zhi-qin, WEI Quan-jia, BAO Tian-you, TU Peng-fei^*. Chemical Constituents of Rheum tanguticum Maxim.ex Balf.[J]. .

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