Chemical Constituents from Ampelopsis grossedentata

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Chemical Constituents from Ampelopsis grossedentata

ZHANG Yan-song, ZHANG Qing-ying, WANG Bin, LI Li-ying, ZHAO Yu-ying^*

1.Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Centre, Beijing 100083, China;
2.Department of Cell Biology and Genetics, Capital University of Medical Sciences, Beijing 100054, China

Received:2006-07-28 Revised:2006-11-10 Online:2006-12-15 Published:2006-12-15
Contact: ZHAO Yu-ying*

Abstract

Abstract: Aim To study chemical constituents from Ampelopsis grossedentata. Methods Separation and purification were performed by using silica gel, polyamide, reverse-phase silica gel, Sephadex LH-20 column chromatographic techniques and silica gel PTLC. Structures were determined by means of physicochemical properties and spectral analysis. Results Four flavonoids were separated and identified from Ampelopsis grossedentata including dihydromyricetin (1), myricetin (2), myricitrin (3), and myricetin-3-O-β-D-galactopyranoside (4). Conclusion Compound 4 was isolated from this genus for the first time, and 2D NMR techniques permitted the correct assignment of ¹H and ¹³C NMR signals of 1.

Key words: Ampelopsis grossedentata, Ampelopsis grossedentata, dihydromyricetin, dihydromyricetin, myricetin, myricetin, myricitrin, myricitrin, myricetin-3-O-β-D-galactopyranoside, myricetin-3-O-β-D-galactopyranoside

CLC Number:

R284.1

R284.2

Supporting:

ZHANG Yan-song, ZHANG Qing-ying, WANG Bin, LI Li-ying, ZHAO Yu-ying^*. Chemical Constituents from Ampelopsis grossedentata[J]. .

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