Synthesis of Phenylpropanoid Glycoside Analogs

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Synthesis of Phenylpropanoid Glycoside Analogs

LI Shu-chun, ZHOU Jing, LI Zhong-jun^*

1. Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China;
2. School of Pharmaceutical Sciences, Shihezi University, Shihezi Xinjiang 832002, China

Received:2003-10-15 Revised:2004-02-10 Online:2004-03-15 Published:2004-03-15
Contact: LI Zhong-jun*

Abstract

Abstract: The regioselective acylation of unprotected phenylethyl glucoside with cinnamoyl chloride leads to 6-OH cinnamoylated glucoside.In this manner, thirteen phenylpropanoid glycoside analogs were designed and prepared.Their structure was confirmed by ¹H NMR and ¹³C NMR spectra.

Key words: medicinal chemistry, medicinal chemistry, regioselective acylation, regioselective acylation, phenylpropanoid glycoside, phenylpropanoid glycoside, glycoside analogs, glycoside analogs, chemical synthesis, chemical synthesis

CLC Number:

R916.4

R917.02

Supporting:

LI Shu-chun, ZHOU Jing, LI Zhong-jun^*. Synthesis of Phenylpropanoid Glycoside Analogs[J]. .

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