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The Chemical Constituents of Diterpenoids from Kaempferia marginata Carey

Yu Jingguang, Yu Donglei, Sun Lan, Zhang Shu, Zheng Caicheng, Chen Yuheng   

  1. 1. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094;
    2. Institute of Meteria Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050
  • Received:2001-02-02 Revised:2001-05-07 Online:2001-06-15 Published:2001-06-15

Abstract: Marginatol (1), a new isopimarene diterpenoid, and five known compounds 8(14),15-sanderacopimaradiene-1α,9α-diol (2), 8(14),15-sanderacopimaradene-1α,6β,9α-triol (3), germacrone (4), trans-ethyl p-methoxycinnamate (5) and n-pentadecane (6) were isolated from the hexane extract of Kaempferia marginata Carey. The structure of marginatol (1) was established as 8(14),15-isopimaradiene-6β-ol on the basis of spectral data (IR, MS, 1H-1H, 13C-1H NMR, NOESY and HMBC). Compounds 2, 3 and 4 were isolated for the first time from this plant.

Key words: Kaempferia marginata Carey, Zingiberaceae, Diterpenoids, Marginatol

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