2D NMR Studies on the Benzodiheteropine and its Cycloaddition Products

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2D NMR Studies on the Benzodiheteropine and its Cycloaddition Products

Yu-Xin Cui, Xiao-Feng Liu, Hai-Tao Wu, Xin-Fu Pan

1. National Research Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083
2. Department of Chemistry, Lanzhou University, Lanzhou 730000

Received:1997-12-12 Revised:1998-06-16 Online:1998-12-15 Published:1998-12-15

Abstract

Abstract: The signals of ¹H NMR and ¹³C NMR for benzodiheteropine 1 and its cycloaddtion products 2~5 were assigned by two dimensional NMR techniques. The characteristics of their structures were analyzed and discussed. The boat conformation of the seven-membered heteroatomic ring in these structures was interpreted on the basis of the spectrum of NOESY as well. The coupling constants of relative protons were in accord with above results.

Key words: Benzodiheteropine, 2D NMR, Conformation, Seven membered heteroatomic ring

Supporting:

Yu-Xin Cui, Xiao-Feng Liu, Hai-Tao Wu, Xin-Fu Pan. 2D NMR Studies on the Benzodiheteropine and its Cycloaddition Products[J]. .

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2D NMR Studies on the Benzodiheteropine and its Cycloaddition Products

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