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Journal of Chinese Pharmaceutical Sciences ›› 2021, Vol. 30 ›› Issue (6): 538-542.DOI: 10.5246/jcps.2021.06.042

• Case report • Previous Articles     Next Articles

A 61-year-old man with bloody purulent cerebrospinal fluid

Yi Zhou, Jun Wang*(), Fengjuan Gao*()   

  1. Department of Emergency Medicine, Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing 210008, China
  • Received:2020-11-18 Revised:2020-12-26 Accepted:2021-02-03 Online:2021-06-29 Published:2021-06-29
  • Contact: Jun Wang, Fengjuan Gao

Abstract:

Staphylococcus aureus meningitis (SAM) is a relatively uncommon but serious disease, accounting for only 1%–9% of cases of bacterial meningitis. In this report, we described a 61-year-old man, whose appearance of CSF was bloody and purulent. CSF test showed extremely elevated WBC count and protein quantification. Bacterial culture demonstrated SAM. Complications included septic shock, acute respiratory failure, and renal failure. Empiric antibiotic treatment was not effective for him. Therefore, we prescribed up to five types of antibiotics. We found that the clinical symptoms, CSF indicators, inflammatory markers, respiratory and renal function got better. The nerve function comparatively recovered well after 6 months of follow-up.

Key words: Staphylococcus aureus meningitis, Septic shock, Cerebrospinal fluid, Antibiotics

Supporting:

Table 1. Changes in inflammatory markers and renal function parameters

Table 2. Changes in CSF indicators