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Journal of Chinese Pharmaceutical Sciences ›› 2020, Vol. 29 ›› Issue (11): 780-792.DOI: 10.5246/jcps.2020.11.071

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The regulatory effects of mulberry leaf and its extract on intestinal function

Yawen Wang, Xiaofeng Duan, Xiaoxiao Cheng, Miaoxin Zhang, Li Li, Ding Zhao*   

  1. School of Pharmacy, Hebei Medical University, Shijiazhuang Hebei 050017, China
  • Received:2020-08-20 Revised:2020-09-15 Online:2020-11-30 Published:2020-09-20
  • Contact: Tel.: +86-311-86266004; Fax: +86-311-85917887; E-mail: zhaodingd@163.com
  • About author:Ding Zhao, Doctor, Professor, doctoral supervisor, is currently the director of the Department of Pharmacognosy, School of Pharmacy, Hebei Medical University, the person in charge of the Department of Traditional Chinese Medicine, and the person in charge of the Medical Plant Research Center of Hebei Medical University.
  • Supported by:
    The Key Generic Technology Research Project of High-Quality Agricultural Development of Hebei Province (Grant No. 20327121D); Biomedical Development and Transformation Research Project of Hebei Province (Grant No. 2020TXZH05) and Science and Technology Research Project of Higher Education Institutions of Hebei Province (Grant No. 2019188).

Abstract:

Since ancient times, mulberry leaf has a prominent intestinal regulatory effect, and the close relationship between intestinal diseases and other diseases has attracted more and more attention. This article reviewed the relevant articles on the mulberry leaf in recent years and summarized the research progress of mulberry leaf’s biological activities and their effects on human intestinal regulation and the corresponding mechanisms. Multiple components in the mulberry leaf can individually or synergistically affect the human intestine, directly and indirectly promote the digestion, absorption, and transport function of the small intestine, adjust the balance of the flora, enhance the barrier function of the intestinal mucosa, improve the immunity of the part, and facilitate the intestine recovery from illness.

 

Key words: Mulberry leaf, Mulberry leaf extract, Intestinal function

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