Silver nitrate restores susceptibility of clinical multidrug resistant gram-negative and gram-positive bacteria to amikacin in vitro

doi:10.5246/jcps.2014.07.066

Journal of Chinese Pharmaceutical Sciences ›› 2014, Vol. 23 ›› Issue (7): 500-503.DOI: 10.5246/jcps.2014.07.066

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Silver nitrate restores susceptibility of clinical multidrug resistant gram-negative and gram-positive bacteria to amikacin in vitro

Cunbao Liu, Weiwei Huang, Xu Yang, Yufeng Yao, Wenjia Sun, Yanbing Ma^*

Department of Molecular Immunology, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China

Received:2014-04-17 Revised:2014-05-08 Online:2014-07-18 Published:2014-05-15
Contact: Tel.: 86-871-68339287, Fax: 86-871-68334483
Supported by:
Peking Union Medical College (PUMC) Youth Fund and the Fundamental Research Funds for the Central Universities, China (Grant No. 333203084).

Abstract

Abstract:

Silver nitrate could inhibit the clinical multidrug resistant isolates at high concentrations (with minimal inhibitory concentrations (MICs) from 32 µM to 64 µM).The activities of amikacin in the presence of sub-lethal silver nitrate (15 µM) were tested for the combinational effects against multidrug resistant clinical isolates in vitro. Silver nitrate restored the susceptibility of drug-resistant Acinetobacter baumannii andmethicillin-resistant Staphylococcus aureus to amikacin. It lowered the MICs of amikacin from >128 µg/mL to (2-16) µg/mL and 32 µg/mL, respectively, and lowered the MICs of amikacin on extended spectrumβ-lactamase-producing Pseudomonas aeruginosa and Escherichia coli from (16-32) µg/mL and 16 µg/mL to (<1-4) µg/mL and <1 µg/mL, respectively.

CLC Number:

R961

Supporting:

Cunbao Liu, Weiwei Huang, Xu Yang, Yufeng Yao, Wenjia Sun, Yanbing Ma. Silver nitrate restores susceptibility of clinical multidrug resistant gram-negative and gram-positive bacteria to amikacin in vitro[J]. Journal of Chinese Pharmaceutical Sciences, 2014, 23(7): 500-503.

References

[1] Xu, Y.; Pang, G.; Gao, C.; Zhao, D.; Zhou, L.; Sun, S.; Wang, B. Antimicrob. Agents Chemother. 2009,53, 1636-1538.

[2] Glynn, F.; Amin, M.; Sheahan, P.; Mc Shane, D. Int. J. Pediatr. Otorhinolaryngol. 2011,75, 81-84.

[3] Bhargava, K.B.; Shirali, G.N.; Abhyankar, U.S.; Gadre, K.C. J. Laryngol. Otol. 1992, 106, 699-701.

[4] Besinis, A.; De Peralta, T.; Handy, R.D. Nanotoxicology. 2014,8, 745-754.

[5] Lwegaba, A.; Phillips, A.; Kiraru, R. West. Indian. Med. J. 2008,57, 63-65.

[6] Boucher, W.; Stern, J.M.; Kotsinyan, V.; Kempuraj, D.; Papaliodis, D.; Cohen, M.S.; Theoharides, T.C. J. Urol. 2008,179, 1598-1602.

[7] Abraham, G.; Pratap, B.; Govindan, P.; Matthew, M. Saudi. J. Kidney. Dis. Transpl. 2007, 18, 231-234.

[8] Gunjan, K.; Shobha, C.; Sheetal, C.; Nanda, H.; Vikrant, C.; Chitnis, D.S. Indian J. Plast. Surg. 2012,45, 374-378.

[9] Oen, I.M.; van Baar, M.E.; Middelkoop, E.; Nieuwenhuis, M.K.; Facial Burns Group. Plast. Reconstr. Surg. 2012, 130, 275e-283e.

[10] Jung, W.K.; Koo, H.C.; Kim, K.W.; Shin, S.; Kim, S.H.; Park, Y.H. Appl. Environ. Microbiol. 2008,74, 2171-2178.

[11] Hwang, I.S.; Lee, J.; Hwang, J.H.; Kim, K.J.; Lee, D.G. FEBS. J. 2012, 279, 1327-1338.

[12] Kyros, L.; Kourkoumelis, N.; Kubicki, M.; Male, L.; Hursthouse, M.B.; Verginadis, I.I.; Gouma, E.; Karkabounas, S.; Charalabopoulos, K.; Hadjikakou, S.K. Bioinorg. Chem. Appl.2010, 386860, doi: 10.1155/2010/386860.

[13] Hadjikakou, S.K.; Ozturk, I.I.; Xanthopoulou, M.N.; Zachariadis, P.C.; Zartilas, S.; Karkabounas, S.; Hadjiliadis, N. J. Inorg. Biochem. 2008, 102, 1007-1015.

[14] Piao, M.J.; Kang, K.A.; Lee, I.K.; Kim, H.S.; Kim, S.; Choi, J.Y.; Choi, J.; Hyun, J.W. Toxicol. Lett. 2011, 201, 92-100.

[15] Chou, T.D.; Gibran, N.S.; Urdahl, K.; Lin, E.Y.; Heimbach, D.M.; Engrav, L.H. Burns. 1999, 25, 549-552.

[16] Stafeeva, K.; Erlanger, M.; Velez-Montoya, R.; Olson, J.L. Clin. Ophthalmol. 2012,6, 2033-2036.

[17] Trop, M.; Novak, M.; Rodl, S.; Hellbom, B.; Kroell, W.; Goessler, W. J. Trauma. 2006, 60, 648-652.

[18] Pariser, R.J. Arch. Dermatol. 1978, 114, 373-377.

[19] Morones, J.R.; Elechiguerra, J.L.; Camacho, A.; Holt, K.; Kouri, J.B.; Ramírez, J.T.; Yacaman, M.J. Nanotechnology. 2005, 16, 2346-2353.

[20] Silver, S.; Phung le, T.; Silver, G. J. Ind. Microbiol. Biotechnol. 2006, 33, 627-634.

[21] Morones-Ramirez, J.R.; Winkler, J.A.; Spina, C.S.; Collins. J.J. Sci. Transl. Med. 2013, 5, 190ra81. doi: 10.1126/scitranslmed.3006276.

[22] Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standard. 9th ed. Wayne, PA: Clinical and Laboratory Standards Institute. 2012.

[23] European Committee on Antimicrobial Susceptibility Testing (EUCAST) Steering Committee. Clin. Microbial. Infect. 2006, 12, 1147-1149.

[24] Deng, M.; Zhu, M.H.; Li, J.J.; Bi, S.; Sheng, Z.K.; Hu, F.S.; Zhang, J.J.; Chen, W.; Xue, X.W.; Sheng, J.F.; Li, L.J. Antimicrob. Agents Chemother. 2014, 58, 297-303.

[25] Falagas, M.E.; Karageorgopoulos, D.E. Clin. Infec. Dis. 2008, 46, 1121-1122.

[26] Hanberger, H.; Edlund, C.; Furebring, M.G.; Giske, C.; Melhus, A.; Nilsson, L.E.; Petersson, J.; Sjölin, J.; Ternhag, A.; Werner, M.; Eliasson, E.; Swedish Reference Group for Antibiotics. Scand. J. Infect. Dis. 2013, 45, 161-175.

Silver nitrate restores susceptibility of clinical multidrug resistant gram-negative and gram-positive bacteria to amikacin in vitro

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