http://jcps.bjmu.edu.cn

Journal of Chinese Pharmaceutical Sciences

• Short communication • Previous Articles     Next Articles

Specific oxidation of honokiol by Cunninghamella echinulata

Zhaohua Wang, Dewu Zhang, Zhengshun Wen, Lin Yang*, Yeling Wang, Shanjun Wei, Jungui Dai*   

  1. 1. College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China
    2. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China
    3. Food and Pharmacy College, Zhejiang Ocean University, Zhoushan 316000, China
  • Received:2013-03-30 Revised:2013-04-16 Online:2013-11-15 Published:2014-01-22
  • Contact: Lin Yang*, Jungui Dai*

Abstract:

Among 37 species of microbial strains, Cunninghamella echinulata AS 3.3400 were found to possess the ability to transform honokiol to (R)-magnolignan C (1) and (S)-magnolignan C (2) by regio-specific oxidation. Among them, 1 was a new compound. The structures of two compounds were determined by the analyses of CD, MS and NMR spectroscopic data.

Key words: Honokiol, Oxidation, Cunninghamella echinulata AS 3.3400

CLC Number: 

Supporting: