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Identification of dimethylamphetamine in a suspect exhibit

Peng Xu, Wen-Si Lin, Chuan-Jun Zhu, Ke-Lin Liu, Ying Chang, Yu-Xin Cui, Xiao-Mei Ling*, Wei Lu   

  1. 1. School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
    2. Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201512, China
    3. Institute of Forensic Science, Ministry of Public Security, Beijing 100038, China
  • Received:2012-01-09 Revised:2012-04-15 Online:2012-06-25 Published:2012-06-25
  • Contact: Xiao-Mei Ling*

Abstract:

N,N-Dimethylamphetamine (DMA) is a methamphetamine (MA) analog and considered as an amphetamine-derived designer drug. In this study, a method of gas chromatography-mass spectrometry (GC-MS) combined with nuclear magnetic resonance spectroscopy (1H and 13C NMR) was developed for the identification of dimethylamphetamine in a suspect exhibit. The results showed that purity of this sample was above 99% by GC-MS area normalization. Therefore, it could be used as a dimethylamphetamine reference substance in drug FTIR analysis, which was successfully applied to identify samples in other similar cases.

Key words: White crystal, Dimethylamphetamine, GC-MS, NMR, FTIR

CLC Number: 

Supporting: