Diterpenoids from the Roots of Agastache rugosa

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Diterpenoids from the Roots of Agastache rugosa

Zhong-Mei Zou, De-Quan Yu, Pu-Zhu Cong

1. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050; 
2. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094

Received:1996-12-12 Revised:1997-04-08 Online:1997-09-15 Published:1997-09-15

Abstract

Abstract: Agastol (2), a new diterpene, was isolated from the roots of Agastache rugosa together with its isomer, named isoagastol (3). Their structures were established on the basis of spectral methods The structures of agastol (2) and isoagastol (3) was elucidated as 11,14-dihydroxy-12-methoxy-19(4→3) abeo-abieta-4(18),8,11,13-tetraen-7-one and 11,14-dihydroxy-12-methoxy-19(4→3) abeo-abieta-3,8,11,13-tetraen-7-one. Isoagastol was isolated for the first time from natural sources.

Key words: Agastache rugosa, Labiatae, Diterpenoids, Agastol, Isoagastol

Supporting:

Zhong-Mei Zou, De-Quan Yu, Pu-Zhu Cong. Diterpenoids from the Roots of Agastache rugosa[J]. .

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Diterpenoids from the Roots of Agastache rugosa

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