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Triterpenoids from the Fruiting Body of Ganoderma lucidum

Fang-Sheng Wang, Hui Cai, Jun-Shan Yang*, Yu-Mei Zhang, Ying-Ju Zhao   

  1. 1. Department of Chemistry, University of Agriculture and Animal Science, PLA, Changchun 130062; 
    2. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094
  • Received:1996-08-23 Revised:1997-04-08 Online:1997-12-15 Published:1997-12-15
  • Contact: Jun-Shan Yang*

Abstract: A new triterpenoid, named ganolactone, was isolated from the CH2Cl2 soluble fraction of the fruiting body of Ganoderma lucidum. Its structure was deduced as 7β-hydroxy-3,11,15-trioxo-lanosta-8-en-24→20s lactone (1) on the basis of spectral analysis (UV, IR, MS, 1H NMR, 13C NMR and 2D NMR) and was confirmed by X-ray diffraction. In addition, three known compounds, ganoderiol A (2), ganoderiol B (3) and ganodermatriol (4), were obtained.

Key words: Ganoderma lucidum, Triterpenoid, Ganolactone

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