Quantitative Analysis of Gadopentetate Dimeglumine Liposomes by Fluorescent Method

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Quantitative Analysis of Gadopentetate Dimeglumine Liposomes by Fluorescent Method

Wang Xianglin, Liu Qian, Chen Chen

1. Shenyang Pharmaceutical University, Shenyang 110015;
2. Liaoning Province Supervise Institute of Feed and Veterinary Drug, Shenyang 110015

Received:1999-08-25 Revised:2000-01-10 Online:2000-12-15 Published:2000-12-15

Abstract

Abstract: A fluorescent method has been developed for the assay of gadopentetate dimeglumine liposomes. The optimal conditions for its determination were investigated. The sample was analyzed at Ex = 275 nm and Em = 313 nm, pH 6.0~8.0. The linear range was between 9.4 μg·ml^-1 and 9.4 mg·ml^-1 and the average recovery was 100.2%. By this method, gadopentetate dimeglumine liposomes has been determined with satisfactory results.

Key words: Fluorescent method, Fluorescent method, Gadopentetate dimeglumine, Gadopentetate dimeglumine, Liposomes, Liposomes

Supporting:

Wang Xianglin, Liu Qian, Chen Chen . Quantitative Analysis of Gadopentetate Dimeglumine Liposomes by Fluorescent Method[J]. .

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Quantitative Analysis of Gadopentetate Dimeglumine Liposomes by Fluorescent Method

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