Abstract: Microbial transformation of gastrodin by Mucor spinosus strain 3.3450, resulted in a product with a transformation rate close to 100 percent. This product was identified as p-hydroxy benzyl alcohol on the basis of its ¹H, ¹³C NMR and EI-MS spectral data. It could be inferred that the enzyme responsible for the biotransforma-tion reaction was a kind of extracellular and constitutive enzyme since the transformation reaction of the substrate could be carried out in cell free extracts of the fermentation broth of the Mucor spinosus.

Key words: Mucor spinosus, Mucor spinosus, Biotransformation, Biotransformation, Gastrodin, Gastrodin, p-Hydroxy benzyl alcohol, p-Hydroxy benzyl alcohol