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Journal of Chinese Pharmaceutical Sciences ›› 2014, Vol. 23 ›› Issue (5): 306-310.DOI: 10.5246/jcps.2014.05.042

• Original articles • Previous Articles     Next Articles

A new indole alkaloid from Nauclea officinalis (Pierre ex Pitard) Merr. et Chun

Xiaoxue Pi1, Kehui Xie1, Guangzhong Tu2, Tianzhi Cai1, Rong Yang1, Qiong Wu1, Hongzheng Fu1*   

  1. 1. State Key Laboratory of Natural Biomimetic Drugs, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100191, China
    2. Beijing Institute of Microchemistry, Beijing 100191, China
  • Received:2013-05-02 Revised:2013-05-21 Online:2014-05-23 Published:2013-06-26
  • Contact: Tel./Fax: 86-10-82805212; E-mail: drhzfu@sina.com
  • Supported by:
    National Natural Science Foundation of China (Grant No. 30973628).

Abstract:

From the aerial parts of Nauclea officinalis (Pierre ex Pitard) Merr. et Chun, one new indole alkaloid paratunamide E (1)has been isolated together with six known indole alkaloids, paratunamide A (2), nauclealotide C (3), nauclealotide A (4), vincosamide (5), strictosamide (6) and naucleamide F (7). Naucleamide F (7) was isolated from Nauclea officinalis for the first time. All of the seven compounds above were elucidated by spectroscopic methods including 1 D and 2 D NMR spectroscopic analyses.

Key words: Nauclea officinalis , Indole alkaloid, Structural identification

CLC Number: 

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