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Synthesis and Antibacterial Effect of New Alkylenedibiguanides

Wang Yi, You Qidong, Zhou Weicheng   

  1. 1. Department of chemical engineering, Nanjing University of Science and technology, Nanjing 210094;
    2. Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009;
    3. Shanghai Institute of Pharmaceutical Industry, Shanghai 200437
  • Received:2002-02-02 Revised:2002-04-15 Online:2002-06-15 Published:2002-06-15

Abstract: Seven new alkylenedibiguanides were synthesized and comfirmed by 1H NMR, MS and elemental analyses. The preliminary test in vitro showed that some of them had potential antibacterial activities.

Key words: Alkylenedibiguanide, Alkylenedibiguanide, Synthesis, Synthesis, Antibacterial, Antibacterial

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