Discovery and development of antiviral drugs

doi:10.5246/jcps.2010.06.056

Abstract

Abstract:

In this short review we summarize the different strategies for discovery and development of antiviral agents, including targeting virus entry into host, virus replication within cells, infant virus assembly and release from the infected cells. The progress on development of various classes of antivirus agents and their potential in virus therapy, mainly targeting human immunodeﬁciency virus (HIV), was also discussed.

Key words: Antivirals, Vaccine, Virus replication, Virus entry, Virus release

CLC Number:

R915

Supporting:

Zhen Zhang, Han Wang, Ling-Yan Du, Kun-Bo Chen, Su-Long Xiao, Fei Yu, Li-He Zhang, De-Min Zhou^*. Discovery and development of antiviral drugs [J]. , DOI: 10.5246/jcps.2010.06.056.

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