To unlock the potential of Elaeagnus mollis, we explored its phytochemical composition, antioxidant properties, cholinesterase inhibition, and anti-HepG2 cell proliferation activity from different plant parts (branch wood, branch bark, and pericarp) using various solvents (water, methanol, ethanol, and n-hexane). The results revealed that water extracts exhibited potent antioxidant effects, while methanol extracts were most effective in inhibiting HepG2 cell growth. n-Hexane extracts demonstrated excellent cholinesterase inhibition. Notably, branch bark extracts were rich in phytochemicals and showed significant biological activity in both cholinesterase inhibition and anti-HepG2 cell proliferation. These results highlight the promising therapeutic potential of Elaeagnus mollis, particularly its branch bark and pericarp, which could serve as valuable resources for the development of novel pharmaceutical products aimed at combating oxidative stress and cancer.
Zhong, H. et al. / J. Chin. Pharm. Sci. 2025, 34 (5), 411–422.
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