Effects of Breviscapine on the Changes in Antioxidant Enzyme Activity Induced by Cerebral Ischemia-reperfusion in Rats

Abstract

Abstract: Effects of breviscapine, the active ingredient isolated from Erigeron breviscapus (Vant) Hand-mazz, on the changes in antioxidant enzyme activity induced by cerebral ischemia-reperfusion in rats were explored. It was found that breviscapine improved the activities of superoxide dismutase (SOD), GSH-peroxidase and catalase, while decreasing the malondialdehyde (MDA) content in the brain, which was benificial in reducing the damage from cerebral ischemia-reperfusion.

Key words: Breviscapine, Cerebral ischemia-reperfusion, Superoxide dismutase, GSHperoxidase, Catalase, Malondialdehyde

Supporting:

Xiao-Xia Chen, Bing He. Effects of Breviscapine on the Changes in Antioxidant Enzyme Activity Induced by Cerebral Ischemia-reperfusion in Rats[J]. .

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Effects of Breviscapine on the Changes in Antioxidant Enzyme Activity Induced by Cerebral Ischemia-reperfusion in Rats

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