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CGC Measurement of Propylene Glycol Content with Bentport Programmed Temperature Vaporizing (PTV) Injector

Ling Xiaomei, Xu Bingjiu   

  1. School of Pharmaceutical Sciences, Beijing Medical University Beijing 100083
  • Received:1998-03-28 Revised:1998-12-10 Online:1999-06-15 Published:1999-06-15

Abstract: This paper describes a CGC method to measure propylene glycol content in injection of 8-chloro-adenosine by injecting into a new PTV injector with bent-port vaporizing tube. This new method has the following advantages over split injection: it results in higher accuracy and precision (RSD ca. 2%, recovery ca. 99%), its analytical Period is short (<7 min), pretreatment of the sample is not necessary, and capillary column is not damaged after hundreds of samples injected. In comparison with PTV techniques published so far, this novel injector is superior in several respects.

Key words: CGC, Propylene glycol in injection, PTV with bent open injector tube

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