Abstract: Five new polyoxygenated cyclohexenes, uvarigranones A (2), B (3), C (6) D (7) and uvarigranol J (5) were isolated from the stems of Uvaria grandiflora. Their structures were established on the basis of spectral data and comparison with known compounds. Among them, the absolute configurations of 2, 5, 6 and 7 were determined from their CD spectra.

Key words: Uvaria grandiflora, Uvaria grandiflora, Polyoxygenated cyclohexene, Polyoxygenated cyclohexene, Uvarigranone A,B,C,D, Uvarigranone A,B,C,D, Uvarigranol J, Uvarigranol J