A case of anaphylactic shock caused by iodixanol during transjugular intrahepatic portosystemic shunt and literature analysis

doi:10.5246/jcps.2023.08.056

Abstract

Abstract:

A 68-year-old patient was admitted to the Department of Gastroenterology at the Second Hospital of Hebei Medical University and underwent a transjugular intrahepatic portosystemic shunt (TIPS) under local anesthesia using iodixanol injection for high pressure imaging. After 15 min, the patient developed symptoms, such as a drop in blood pressure and skin itching, indicating anaphylactic shock. We promptly administered emergency measures, including antiallergic and anti-shock treatment. The patient’s vital signs gradually recovered, and the symptoms of anaphylactic shock disappeared. Ultimately, the operation was successfully completed without any complications. This article analyzed the rescue measures and treatment of a patient who experienced anaphylactic shock due to an iodixanol injection during TIPS. The purpose was to increase awareness of the safe use of iodixanol. When iodixanol is used for contrast, a patient may experience a drop in blood pressure and skin itching within a short period of time, potentially leading to anaphylactic shock. During the operation, it is crucial to closely monitor the patient’s condition and promptly recognize allergic symptoms for effective treatment. This is the key to rescuing a patient experiencing anaphylactic shock.

Key words: Transjugular intrahepatic portosystemic shunt, Iodixanol injection, Anaphylactic shock, Rescue measures

Supporting:

Weiwei Xie, Jian Liu, Yuqian Zhang, Zhiqing Zhang, Yiran Jin. A case of anaphylactic shock caused by iodixanol during transjugular intrahepatic portosystemic shunt and literature analysis[J]. Journal of Chinese Pharmaceutical Sciences, 2023, 32(8): 677-682.

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