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Structural elucidation of a new cembranoid diterpene from the Chinese soft coral Sarcophyton sp.

Wei Bie, Zhi-Wei Deng, Min-Juan Xu, Wen-Han Lin*   

  1. 1. The State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China;
    2. Analytical and Testing Center, Beijing Normal University, Beijing 100875, China
  • Received:2008-03-10 Revised:2008-08-10 Online:2008-09-15 Published:2008-09-15
  • Contact: Wen-Han Lin*

Abstract:

To investigate the cembranoid diterpenes from the soft coral Sarcophyton sp. collected in the South China Sea. Repeatedly column chromatography was performed for the isolation and purification. The structures were elucidated on the basis of extensive spectral data (IR, MS, 1D- and 2D-NMR) analysis by comparing with literature data. A new cembranoid diterpene namely sarcophyolide A (1), together with 7α, 8β-dihydroxydeepoxysarcophine (2) were isolated from this species. The cembranoid diterpenes with γ-lactone could be chemotaxonomic markers of Sarcophyton sp.

Key words: Sarcophyton sp., Sarcophyton sp., Cembranoid diterpene, Cembranoid diterpene, Sarcophyolide A, Sarcophyolide A, Structural elucidation, Structural elucidation

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