http://jcps.bjmu.edu.cn

• Full Papers • Previous Articles     Next Articles

Total Synthesis of Anisodine

WU Yan-fen, LU Qiang, Lü Wen, ZHANG Wen-sheng*   

  1. Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Peking Un iversity, Beijing 100083, China
  • Received:2004-10-30 Revised:2005-02-10 Online:2005-03-15 Published:2005-03-15
  • Contact: ZHANG Wen-sheng*

Abstract: Aim To design a practical synthetic route of anisodine. Methods Sta rting from 3α-hydroxy-6β-acetyltropine, anisodine was synthesized in 11 steps. Result Anisodine was obtainded with an overall yield of 2.6%. Conclusion Total synthetic route of anisodine was achieved whi ch may afford a possible route for commercial preparation of anisodine.

Key words: anisodine, anisodine, tropine alkaloid, tropine alkaloid, total synthesis, total synthesis

CLC Number: 

Supporting: