Lignanoids from Solanum lyratum

doi:10.5246/jcps.2018.04.030

Journal of Chinese Pharmaceutical Sciences ›› 2018, Vol. 27 ›› Issue (4): 289-294.DOI: 10.5246/jcps.2018.04.030

• Short communication • Previous Articles

Lignanoids from Solanum lyratum

Yunling Xu^1,2,3, Yajuan Xu³, Haoxia Shi^1,2,3, Yue Liu^3*, Tunhai Xu^1,2*

1. Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
2. Health Cultivation Laboratory of Ministry of Education, Beijing 100029, China
3. Key Laboratory of Effective Substances of Traditional Chinese Medicine, Jilin Academy of Chinese Medicine Sciences, Changchun 130012, China

Received:2018-01-13 Revised:2018-02-23 Online:2018-04-30 Published:2018-03-15
Contact: Tel.: +86-010-64286935, E-mail: thxu@163.com
Supported by:
Science and Technology Department Plan of Jilin Province, China (Grant No. 20160101341JC and 20160622010JC).

Abstract

Abstract:

In the present study, we aimed to investigate the chemical constituents from Solanum lyratum.The constituents were separated by column chromatography on silica gel, Sephadex LH-20 and preparative HPLC. Their structures were elucidated by spectroscopic means. A total of 13 compounds were isolated fromS. lyratumand identified as syringin (1), (+)-isolariciresinol (2), (+)-syringaresinol (3), leptolepisol D (4),(–)-secoisolariciresinol (5), (–)-epi-syringaresinol (6),aviculin(7), zhebeiresinol(8), ciwujiatone(9), (–)-(7′S,8S,8′R)-4,4′-dihydroxy-3,3′,5,5′-tetramethoxy-7′,9-epoxylignan-9′-ol-7-one(10),(+)-lariciresinol(11), (+)-pinoresinol (12) and (+)-medioresinol (13). All the compounds were isolated from S. lyratumfor the first time.

Key words: Solanum lyratum, Lignanoids, Syringaresinol, Lariciresinol

CLC Number:

R284

Supporting:

Yunling Xu, Yajuan Xu, Haoxia Shi, Yue Liu, Tunhai Xu. Lignanoids from Solanum lyratum[J]. Journal of Chinese Pharmaceutical Sciences, 2018, 27(4): 289-294.

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Lignanoids from Solanum lyratum

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